Figure 6
Effect of GQDGLAGPK on expression of CD4+ T cells in the lacrimal glands of experimental dry eye mouse model. (A) The sections were immunostained with specific antibodies for CD4 before desiccation stress, immediately after desiccation stress for 10 days, and 10 days after treatment with Hyp-GQDGLAGPK, cyclosporine, diquafosol, and sodium hyaluronate eye drops. Scale bar = 100 μm. (B) The stained area of the photograph was analyzed using ImageJ® and calculated in terms of the fold of the control. Values are mean ± SD (n = 5~6 eyes). The results are statistically significant by analysis of variance with the Tukey test at *p < 0.05 compared with baseline, # p < 0.05 compared with DS 10d and † p < 0.05 vs corresponding value in the normal saline group. Con = control; DS 10d = immediately after desiccation stress for 10 days; NS = normal saline; 10mer = Hyp-GQDGLAGPK; Cys = cyclosporine; Diq = diquafosol; HA = sodium hyaluronate; CD4 = cluster of differentiation 4.
