Table 1 Comparing the efficacy of Hyp-GQDGLAGPK and commercial medicines in an experimental dry eye mouse model.

From: Anti-inflammatory effect of hydroxyproline-GQDGLAGPK in desiccation stress-induced experimental dry eye mouse

 

Hyp-GQDGLAGPK

Cyclosporine

Diquafosol

Sodium hyaluronate

Tear production

+++

+++

+++

+

Epithelium stabilization

+++

+

+++

+

Goblet cells

++

++

−

−

Anti-inflammation

+++

++

+

−

  1. The effects of Hyp-GQDGLAGPK and commercial medicines on tear production, epithelium stabilization, goblet cell density, and expression of inflammatory markers associated with dry eye disease are indicated as −, +, ++ and +++. No effect expressed as −; + indicated significantly different at DS 10d, but no difference with normal saline; ++ indicated significantly different with DS 10d and normal saline group; +++ indicated similar to baseline.
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