Figure 4 | Scientific Reports

Figure 4

From: RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output

Figure 4

Gluconeogenic genes are differentially expressed in the diabetic mice liver and correlate with H19 expression levels. (a) Network representation of the biological pathways enriched among 2284 genes that correlated with H19 expression. (b) Mean expression pattern of all glycolysis and gluconeogenesis genes between diabetic (db/db) and normal (db/+ ) mice livers as obtained from the RNA sequencing analysis. The bars in blue depict NLP (negative logarithm (log10) of the p-value) of differential expression. Highlighted gene names indicate genes specific to the gluconeogenic pathway.

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