Figure 1
From: TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria
Inflammatory cell infiltration in P. berghei infected placenta. Images from the placental labyrinth layer from WT infected mice. Transmission electron microscopy (TEM) in the labyrinth region (A,B) showing the maternal-fetal interface with presence of iRBCs in the maternal blood space (MBS), but not in fetal blood vessels (FBV). Bar in (A) = 10 µm and (B) = 2.5 µm. Immunofluorescence of placentas (C,D) from infected WT mice with GFP-labelled P. berghei NK65GFP (green), DAPI (blue) and anti-CD11b (red) revealing the accumulation of parasites (C) and infiltration of monocytes/macrophages (D) on maternal blood sinuses; Bar in (C,D) = 100 µm. (GC) Giant cell.
