Figure 6

Effects of TonEBP haploinsufficiency on iba1 expression in the hippocampus of HFD/STZ-treated mice. Representative micrographs of iba1 immunoreactivity in the hippocampal CA3 (a) and CA1 (b) regions. The intensity of iba1 immunoreactivity in the hippocampal CA3 (c) and CA1 (d) regions was measured and presented as the fold change. Data are presented as the mean ± SEM. *P < 0.05 vs. control (CTL) normal diet-fed mice; ^† P < 0.05 vs. DM WT mice. Scale bar = 50 μm.