Figure 3 | Scientific Reports

Figure 3

From: Octahedron Iron Oxide Nanocrystals Prohibited Clostridium difficile Spore Germination and Attenuated Local and Systemic Inflammation

Figure 3

Spore germination was significantly inhibited in Fe3-δO4-treated pathogenic strains of C. difficile. Spores from two pathogenic strains of C. difficile (CCUG 19126 and ATCC BAA-1805) were treated for 20 minutes with various concentrations of Fe3-δO4 nanoparticles and then with 10 mM taurocholate to induce spore germination. Spore germination was effectively inhibited in the two Fe3-δO4-treated pathogenic strains, as it was in the nonpathogenic CCUG 37780 strain. (***P < 0.001, *P < 0.05; one-way analysis of variance [ANOVA] followed by Tukey’s Multiple Comparison test).

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