Table 1 Selected M. tuberculosis mannoproteins with high confidence glycopeptidomics identification.
Peptide sequence | Experimental Mass (Da) | Calculated Mass (Da) | Delta (Da) | Hexose number | Peptide score | Protein Access # | Rv gene | Gene Name | Protein description | required for | |
|---|---|---|---|---|---|---|---|---|---|---|---|
in-vitro growthd | in-vivo growthe | ||||||||||
D100C*VAAT aQAPDAGAMSASMQK119 b | 2170,9 | 2008,9 | 162,1 | 1 | 121,2 | O07419 | Rv0175 | mce1F | Mce associated membrane protein | − | + |
P39AGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSK74 | 3544,7 | 3382,6 | 162,1 | 1 | 28,62 | O07242 | Rv0315c | β-1,3-glucanase precursor | − | + | |
T 47 TTPSGPVPPVSEAAR62 | 1889,9 | 1565,8 | 324,1 | 2 | 55,3 | O53850 | Rv0838 | lpqR | D-alanyl-D-alanine dipeptidase | − | nr |
V228QVTKPPVS 236 | 1115,6 | 953,6 | 162,1 | 1 | 24,94 | P9WK45 | Rv1411cc | lprG | Lipoarabinomannan carrier protein LprG | − | + |
Q164PFSLQLIGPPPSPVQR180 b | 2022,1 | 1860,0 | 162,1 | 1 | 49,06 | I6XHD1 | Rv3491c | Predicted secreted protein | − | nr | |
