Table 2 Summary of canonical signal transduction pathways.
Canonical pathway | Pathway id | AB81_exclusive network | HK2_exclusive network | Intersection AB81_HK2 | |||
|---|---|---|---|---|---|---|---|
p-value | Adj p-value | p-value | Adj p-value | p-value | Adj p-value | ||
Alk in cardiac myocytes | BioCarta:alkpathway | 1.73E-04 | 0.00E+00 | 4.23E-04 | 1.00E-03 | ||
BMP2 signaling pathway(through Smad) | INOH:BMP2_signaling_TGF-beta_MV | 8.70E-03 | 8.00E-03 | 2.17E-04 | 0.00E+00 | ||
Circadian rhythm pathway | NCI-nature:circadianpathway | 2.30E-03 | 2.00E-03 | ||||
HIF-1-alpha transcription factor network | NCI-nature:hif1_tfpathway | 8.80E-05 | 0.00E+00 | 6.26E-04 | 0.00E+00 | ||
HIF-2-alpha transcription factor network | NCI-nature:hif2pathway | 1.79E-03 | 2.00E-03 | 1.80E-03 | 2.00E-03 | 1.77E-04 | 0.00E+00 |
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha | NCI-nature:hif1apathway | 6.12E-03 | 1.00E-02 | 3.21E-03 | 3.00E-03 | ||
ID | CellMap:ID | 3.40E-04 | 0.00E+00 | 7.95E-03 | 6.00E-03 | ||
Mets affect on macrophage differentiation | BioCarta:etspathway | 2.73E-03 | 2.00E-03 | ||||
Angiopoietin receptor Tie2-mediated signaling | NCI-nature:angiopoietinreceptor_pathway | 1.02E-03 | 2.00E-03 | ||||
Estrogen responsive protein efp controls cell cycle and breast tumors growth | BioCarta:efppathway | 2.33E-03 | 0.00E+00 | ||||
nfkb activation by nontypeable hemophilus influenzae | BioCarta:nthipathway | 2.08E-03 | 3.00E-03 | ||||
NOTCH | CellMap:NOTCH | 1.84E-03 | 3.00E-03 | ||||
AP-1 transcription factor network | NCI-nature:ap1_pathway | 9.35E-06 | 0.00E+00 | ||||
EGFR1 | CellMap:EGFR1 | 5.30E-03 | 1.00E-03 | ||||
Mapkinase signaling pathway | BioCarta:mapkpathway | 4.92E-03 | 5.00E-03 | ||||
Overview of telomerase protein component gene htert transcriptional regulation | BioCarta:tertpathway | 5.37E-03 | 7.00E-03 | ||||
Regulation of retinoblastoma protein | NCI-nature:rb_1pathway | 3.57E-03 | 4.00E-03 | ||||
Signaling mediated by p38-alpha and p38-beta | NCI-nature:p38alphabeta-downstreampathway | 1.00E-04 | 0.00E+00 | ||||
