Figure 5
From: Structure formation during translocon-unassisted co-translational membrane protein folding
MPEx46 analysis of DsbB and GlpG. The translocon TM analysis (top row, blue) analyses the TM transfer free energetics based on translocon-mediated TM helix assembly. The Octanol-Interfacial scale (Oct-IF, bottom row, green) identifies segments that tend to prefer a TM helix conformation relative to an unfolded interfacial location. The translocon TM analysis and Oct-IF analysis for GlpG (left) are remarkably similar. The hydropathy analysis for DsbB (right) reveals substantial differences between the translocon TM and Oct-IF analysis, specifically for the polypeptide region (48–105 residues) corresponding to the second and third TM (TM-2 and TM-3, respectively).
