Figure 2
G. muris infection in C57BL/6 WT mice has an impact on the circadian clock. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway for the circadian clock (©Kanehisa Laboratories)50. Red and green respectively indicates transcriptional up- or down-regulation in C57BL/6 WT infected mice compared to C57BL/6 WT uninfected control mice, as identified by RNA-seq. (B) Relative mRNA expression levels of the circadian clock associated genes Ciart, Per1, Per2 and Per3 in G. muris infected C57BL/6 WT mice as measured by qRT-PCR at day 21 post infection compared to uninfected control mice (*p < 0.05, **p < 0.01).
