Table 3 Top 15 most upregulated genes as identified by RNA-seq that differentially respond to infection in C57BL/6 WT infected mice versus C57BL/6 IL-17RA-KO infected mice (A) and also in WT infected mice versus WT uninfected controls (B).
Gene symbol | Gene name | RefSeq ID | Fold change A | Fold change B |
|---|---|---|---|---|
TMEM27 | Transmembrane protein 27 | NM_020626 | 47,69 | 3,49 |
MBL2 | Mannose-binding lectin 2 | NM_010776 | 29,25 | 6,47 |
DPPA3 | Developmental pluripotency-associated 3 | NM_139218 | 13,09 | 2,97 |
NFE2 | Nuclear factor, erythroid derived 2 | NM_008685 | 11,45 | 2,86 |
GSDMC | Gasdermin C | NM_031378 | 9,33 | 3,90 |
GP1BA | Glycoprotein 1b, alpha polypeptide | NM_010326 | 8,61 | 3,52 |
RGS22 | Regulator of G-protein signalling 22 | NM_001195748 | 7,25 | 3,54 |
GSDMC2 | Gasdermin C2 | NM_177912 | 7,16 | 3,75 |
NMU | Neuromedin U | NM_019515 | 6,76 | 2,18 |
CCDC129 | Coiled-coil domain containing 129 | NM_001081665 | 5,94 | 2,54 |
GPR123 | Adhesion G protein-coupled receptor A1 | NM_177469 | 5,60 | 3,37 |
ANG4 | Angiogenin, ribonuclease A family, member 4 | NM_177544 | 5,56 | 7,20 |
DUOX2 | Dual oxidase 2 | NM_177610 | 5,55 | 4,10 |
RAB44 | RAB44, member RAS oncogene family | NM_001002786 | 5,37 | 4,26 |
MRGPRA9 | MAS-related GPR, member A9 | NM_001288801 | 5,20 | 7,77 |
