Figure 3

Blood test results from mice sacrificed post intravesical exposure to PBS, QD, and anti-CD47-QD. The pink region represents the normal range for mice as provided by the vendor, and the blue region represents the range (±1 standard deviation from the mean) we obtained in this study for our 3 untreated mice. Areas of overlap between the two are purple. Error bars represent one standard deviation above the mean. (a) WBC, white blood cells. (b) RBC, red blood cells. (c) Hb, hemoglobin. (d) AST, aspartate aminotransferase. (e) ALT, alanine aminotransferase. (f) BUN, blood urea nitrogen. (g) Cr, creatinine. The results show no changes in blood count, liver enzymes and kidney function at 1-, 3- and 7-days after QD or anti-CD47-QD instillation. The table indicates number of mice analyzed at each time point.