Table 1 Characteristics of BT and AT siblings from the AMDTSS and KHTS*.

From: Twin birth changes DNA methylation of subsequent siblings

 

AMDTSS

KHTS

BT siblings

AT siblings

P-value

BT siblings

AT siblings

P-value

N

112

103

 

27

15

 

Age, mean ± SD

59.9 ± 7.3

52.9 ± 7.1

 < 0.01

46.2 ± 6.1

42.5 ± 5.0

0.05

Sex, N (%)

  

  

0.96

 Females

112 (100.0)

103 (100.0)

 

16 (59.3)

9 (60.0)

 

 Males

0

0

 

11 (40.7)

6 (40.0)

 

BMI, mean ± SD

27.5 ± 5.8

26.6 ± 6.0

0.26

24.8 ± 3.0

22.8 ± 3.4

0.06

Smoking, N (%)

  

0.91

  

0.73

 Never

65 (58.0)

58 (56.3)

 

17 (63.0)

11 (73.3)

 

 Ever

47 (42.0)

45 (43.7)

 

10 (37.0)

4 (26.7)

 

Alcohol, N (%)

  

0.83

  

1.00

 Never

43 (38.4)

42 (40.8)

 

5 (0.19)

3 (0.20)

 

 Ever

69 (61.6)

61 (59.2)

 

22 (0.81)

12 (0.80)

 
  1. *BT: before twin birth; AT: after twin birth; AMDTSS: Australian Mammographic Density Twins and Sisters Study; KHTS: Korean Healthy Twin Study; SD: standard deviation.
  2. P-value for compare the characteristic between BT and AT siblings within each study.