Table 1 Onset temperature and Tm of the BsAb (CD3×HER2) and it’s parental mAbs.

From: Efficient generation of bispecific IgG antibodies by split intein mediated protein trans-splicing system

Antibody

Onset

Tm

CD3×HER2 BsAb

58.5°C

67.5°C

Trastuzumab

60.9°C

69.6°C

Anti-CD3 mAb

57.6°C

66.8°C

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