Table 2 Anatomic location of the significant clusters revealing a loss of gray matter volume in the studied groups.

Contraste	Cluster	Laterality	Size in mm³	p-value	Coordinates (x, y, z)
pro-DLB < HC	Medial frontal gyrus	R	1545	0.042	7	58	29
	(Superior and orbital parts)	R	1545	0.042	7	58	29
	Insula	L	1514	0.036	−38	10	−7
	Posterior insula – Claustrum	R	741	0.039	37	−4	−2
	Anterior insula	R	190	0.047	33	27	−2
mild-DLB < HC	Insula – Claustrum	L	2022	0.034	−35	−9	−5
mild-AD < HC	Parahippocampal gyrus	L	8613	0.023	−22	−5	−21
	Hippocampus – Amygdala
	Putamen – Insula
	Temporal pole
	Parahippocampal gyrus	R	7306	0.020	24	−3	−21
	Hippocampus – Amygdala
	Putamen – Insula
	Temporal pole
	Inferior temporal gyrus	L	3904	0.025	−56	−12	−30
	Inferior temporal gyrus	R	406	0.041	55	−29	27
	Fusiform gyrus	L	96	0.049	−29	−8	−36
	Superior temporal sulcus	L	76	0.049	−55	−12	−15
mild-AD < mild-DLB	Middle temporal gyrus	L	421	0.046	−56	−12	−30

pro-DLB, dementia with Lewy bodies at the prodromal stage; mild-DLB, dementia with Lewy bodies at the stage of dementia; pro-AD, Alzheimer’s disease at the prodromal stage; mild-AD, Alzheimer’s disease at the stage of dementia; HC, healthy controls. The clusters are named according to the Automated Anatomical Labeling template. Laterality: L, left hemisphere; R, right hemisphere. P-values are the mean corrected p-value in the cluster. Coordinates are in millimeters in the Montreal National Institute (MNI) space.

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