Figure 2 | Scientific Reports

Figure 2

From: A novel method for genome-wide profiling of dynamic host-pathogen interactions using 3′ end enriched RNA-seq

Figure 2

Sequencing reads and poly(A) sites in host genes. (A) Genomic locations of sequencing reads. The genomic annotation of host was downloaded from UCSC by selecting Ensembl Genes track and the 3′ UTR tail of these genes were annonated as Ensembl. (B) Distribution of poly(A) sites in genome. (C) Signal using of poly(A) sites. If none of common hexamers was identified in upstream of poly(A) sites, it was classified into none category. (D) Genes with different numbers of tandem poly(A) sites. (E) Examples of genes with two and three 3′ UTR isoforms (MAP3K8 and CABP1). (F) Histograms of the distances between stop codons and poly(A) sites in genes with single poly(A) sites and distances between stop codons and closest poly(A) sites and longest poly(A) sites in genes with APA in the 3′-end.

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