Table 2 General physicochemical properties of antibiotic substrates of AcrB and AcrD.

From: Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters

Antibiotic substrate type (Physicochemical property)

E. coli

AcrB

AcrD

Hydrophobic

+

−

Hydrophilic

−

+

Amphiphilic

+

+

Back to article page