Figure 5
From: CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells
Activation of CXCR7 induces angiogenesis in vivo. (A) Mice were injected with Matrigel-containing CXCL12 (100 ng/mL) or TC14012 (30 μM) as indicted to induce angiogenesis in vivo for 10 days, Matrigel plugs were removed. (B) Representative HE staining of Matrigel plugs from control group, CXCL12 treated group and TC14012 treated group. Magnification 40×. (C) Quantification of hemoglobin content in the Matrigel plugs. (D) Quantification of the number of vessels in sections B. Values are shown as mean ± SD; *p < 0.05/**p < 0.01 versus control.
