Figure 3
From: Octacosanol restores stress-affected sleep in mice by alleviating stress
Changes in sleep architecture after octacosanol administration in mice. Graphs show qualitative analysis thus sleep architecture following p.o. administration of vehicle (gray bars), octacosanol (200 mg/kg; red bars), and control (open bars) during initial 6 h of dark phase. Graphs represent changes in number of episodes (bouts; A), mean duration (B) of wake, REM, and NREM sleep. (C) Graph shows stage transition from NREM to wake (NR→W), wake to NREM (W→NR), NREM to REM (NR→R) and REM to wake (R→W). (D–F) Graph shows the EEG power density of NREM (D) and REM (E) sleep over 6 h dark phase, and wake (F) over 1 h following vehicle (gray line) and octacosanol (red line) administration in mice. Data presented as mean ± SEM; n = 5–8; *p ≤ 0.05, vs vehicle, by using one-way ANOVA followed by Scheffe post hoc test.
