Table 4 MRI measures of healthy controls, the cognitively preserved and cognitively impaired patient groups.

BPF

0.88 (0.003)

0.88 (0.003)

0.87 (0.004)^**

GMF

0.51 (0.004)

0.49 (0.004)^*

0.51 (0.006)

WMF

0.37 (0.004)

0.38 (0.004)

0.36 (0.006)^##

FHLV, ml

NA

5.5 (0.8)^*

6.8 (1.2)^*

Cortical thickness, mm

3.02 (0.02)

2.88 (0.02)^***

2.86 (0.03)^***

 Frontal

3.11 (0.03)

2.94 (0.03)^***

2.92 (0.04)^**

 Parietal

2.92 (0.03)

2.77 (0.02)^***

2.73 (0.04)^***

 Temporal

3.37 (0.03)

3.19 (0.03)^***

3.17 (0.05)^**

 Occipital

2.75 (0.02)

2.61 (0.02)^***

2.62 (0.03)^*

Deep gray matter volume (10³ ml)

 Thalamus

9.9 (0.14)

9.85 (0.13)

9.17 (0.19)^**,#

 Putamen

5.98 (0.09)

5.9 (0.09)

5.64 (0.13)

 Pallidum

2.23 (0.07)

2.3 (0.07)

2.25 (0.1)

 Hippocampus

4.73 (0.09)

4.89 (0.09)

4.58 (0.13)

 Accumbens

5.2 (0.2)

5.16 (0.19)

4.42 (0.28)

 Amygdala

1.4 (0.04)

1.38 (0.04)

1.4 (0.05)

 Caudate

4.64 (0.09)

4.88 (0.09)

4.47 (0.13)^#

DTI: whole NAWM skeleton

 Mean FA (10^–1)

5.21 (0.04)

4.96 (0.04)^***

4.75 (0.06)^***,#

 Mean MD (10^–4 mm²/s)

7.89 (0.06)

8.09 (0.06)

8.45 (0.09)^***,##

 Mean AD (10^–4 mm²/s)

12.72 (0.06)

12.81 (0.06)

12.99 (0.08)^*

 Mean RD (10^–4 mm²/s)

5.49 (0.08)

5.77 (0.07)^*

6.25 (0.11) ^***,##