Table 6 Logistic regression model describing predictors of bronchopulmonary dysplasia.

From: Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene

Variable

GWAS

Internal replication populations joint

All Finnish populations joint

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

SNP rs11265269

3.37 (1.89–6.00)*

3.76 × 10–5

1.45 (1.02–2.05)*

0.038

1.82 1.36–2.43)*

5.32 × 10−5

Gestational age†

0.83 (0.68–1.02)

0.076

0.67 (0.60–0.75)

5.31 × 10−12

0.70 (0.63–0.77)

2.67 × 10−13

SGA‡

3.50 (1.58–7.76)

1.98 × 10–3

2.65 (1.64−4.26)

6.45 × 10−5

2.86 (1.91–4.28)

3.05 × 10−7

  1. Definition of abbreviations: GWAS, genome-wide association study; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; SGA, small for gestational age.
  2. *Odds ratio for minor allele under additive model.
  3. †As continuous variable in the model.
  4. ‡Defined as birthweight Z-score of ≤−2 SD. Birthweight Z-score describes distribution of birthweight at given length of gestation in SD.
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