Table 2 Main association results for BP traits in the overall HCHS/SOL discovery sample.

From: Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos

Trait

rsID

Chr

position

A1

A2

type

EAF

beta

SE

p-value

heterogeneity p-value

Gene

MAP

rs1458038

4

81164723

T

C

g

0.24

0.97

0.178

5.22E-08

0.84

FGF5

SBP

rs143503553

5

159593663

G

C

i

0.01

7.994

1.475

5.94E-08

0.26

 

SBP

rs190705571

6

25693887

T

G

i

0.65

1.268

0.226

2.16E-08

0.21

SCGN

MAP

rs190705571

6

25693887

T

G

i

0.65

0.827

0.16

2.29E-07

0.19

SCGN

MAP

 

10

84135292

CA

C

i

0.3

1.031

0.184

1.93E-08

0.59

NRG3

DBP

 

10

84135292

CA

C

i

0.3

0.938

0.162

7.05E-09

0.54

NRG3

SBP

rs73156692

12

101608695

A

G

i

0.16

1.646

0.303

5.44E-08

0.37

SLC5A8

PP

rs117386367

17

53098512

A

G

i

0.01

5.006

0.931

7.61E-08

0.11

 
  1. For each locus associated with a BP trait we provide the lead SNP. The effect size, beta, is of the effect allele A1. EAF is the frequency of A1 in the overall sample. Imputation “type” is either ‘i’ (imputed) or ‘g’ (genotyped). The effect estimates, standard errors (SEs) and heterogeneity test p-values were obtained from a fixed-effects meta-analysis across the genetic analysis groups.
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