Table 3 Association results in analyses stratified by Mainland and Caribbean subgroups.

From: Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos

Trait

rsID

Chr

position

A1

A2

type

Caribbean

Mainland

overall

heterogeneity

EAF

beta

SE

p-value

EAF

beta

SE

p-value

p-value

p-value

SBP

rs113204208

1

90549106

G

C

i

0.01

7.919

1.416

2.23E-08

0.01

1.363

2.037

5.03E-01

6.83E-07

<0.001

DBP

rs78701042

1

115841602

T

C

i

0.01

5.443

0.957

1.31E-08

<0.005

0.035

1.927

9.85E-01

3.40E-07

0.03

PP

rs11466481

3

30664148

T

C

i

0.04

3.182

0.568

2.08E-08

0.01

0.336

0.916

7.13E-01

7.10E-07

<0.001

  1. For each locus associated with a BP trait in one of the Mainland or Caribbean subgroups we provide the lead SNP. Imputation “type” is either ‘i’ (imputed) or ‘g’ (genotyped). The effect size, beta, is of the effect allele A1. EAF is the frequency of A1 in the appropriate subsample. The effect estimates, standard errors (SEs) and heterogeneity p-values were obtained from a fixed-effects meta-analysis across the genetic analysis groups.
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