Table 4 Association testing results in follow-up studies.

From: Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos

trait

rsID

Chr

position

A1

HCHS/SOL

COGENT

Pelotas

EA meta

EAF

beta

p-value

EAF

beta

p-value

EAF

beta

p-value

beta

p-value

SBP

rs113204208

1

90549106

G

0.01

5.78

6.83E-07

0.06

−0.48

2.28E-01

0.01

−4.28

3.20E-02

  

DBP

rs78701042

1

115841602

T

0.01

4.38

3.40E-07

0.04

0.28

3.35E-01

0.01

4.24

8.56E-03

  

PP

rs11466481

3

30664148

T

0.02

2.4

7.10E-07

0.15

−0.04

8.49E-01

0.03

−0.16

8.15E-01

  

SBP

rs143503553

5

159593663

G

0.01

7.99

5.94E-08

   

0.01

0.8

7.41E-01

0.42

3.70E-01

SBP

rs9366626*

6

25684953

G

0.55

1.18

8.75E-08

0.7

0.14

5.00E-01

0.6

−0.5

1.12E-01

−0.16

1.50E-02

MAP

rs9366626*

6

25684953

G

0.55

0.79

3.04E-07

   

0.6

−0.29

2.56E-01

−0.31

2.25E-02

DBP

 

10

84135292

CA

0.3

0.94

7.05E-09

      

0.06

3.15E-01

MAP

rs7909484*

10

84206002

T

0.4

0.68

1.50E-05

      

0.15

3.37E-01

DBP

rs7909484*

10

84206002

T

0.4

0.6

1.55E-05

      

0.01

8.97E-01

SBP

rs73156692

12

101608695

A

0.16

1.65

5.44E-08

0.16

0.11

6.85E-01

0.2

−0.53

1.71E-01

0.21

7.05E-03

PP

rs117386367

17

53098512

A

0.01

5.01

7.61E-08

   

0.01

2.38

6.76E-02

−0.1

8.05E-01

  1. For each locus reported in Tables 2 and 3 (associated with a BP trait in either the overall sample, or one of the Mainland or Caribbean groups), and available in the follow-up studies, we provide effect allele frequency (EAF), estimated effect size (beta), and p-value in both the HCHS/SOL (from analysis in the overall sample) and the follow-up cohorts. *In a few instances, we report available proxy SNP rather than the lead SNPs, or more weakly associated trait.
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