Figure 4

Multivariate data analysis of bile acid profiles in sera and liver. The PLS-DA score plots demonstrated complete separation of samples between groups in sera (a) and liver (b). The black circles represented the control, while the red and blue circles represented the Geniposide 100 mg/kg and 300 mg/kg group respectively, as indicated on the plots. According to PLS-DA score plots, LV1 scores in sera and liver were presented, respectively. The VIP plots of PLS-DA highlighted the discriminatory species in sera (c) and liver (d). *p < 0.05, ***p < 0.001, compared with the control group.