Table 4 The detected QTL and the most significant SNP for female fertility traits in the meta-analysis across populations.

From: Genome-wide Association Studies for Female Fertility Traits in Chinese and Nordic Holsteins

 

QTL boundaries

Most significant SNP1

BTA

Trait1

Left2 (bp)

Right3 (bp)

N4

Position5 (bp)

SNP

MAF6

P-value

Genes7

1

CRc

78,034,231

78,511,271

1

78,034,231

rs29009958

0.35, 0.41

3.92E-06

TP63

13

IFLc

31,524,626

31,524,626

1

31,524,626

rs41604666

0.49, 0.48

3.67E-06

RSU1

17

CRh

67,245,920

67,941,337

2

67,245,920

rs41848120

0.48, 0.46

2.54E-06

PIWIL3, MYO18B

23

CRc

49,651,909

50,036,208

1

50,036,208

rs110076231

0.38, 0.45

4.79E-05

PRPF4B, PXDC1

28

ICF

34,021,273

34,596,949

1

34,429,786

rs110181893

0.29, 0.42

5.22E-05

ENSBTAG00000013264, ZMIZ1

  1. 1CRh = conception rate at first insemination in heifers; ICF = interval from calving to first insemination; IFLc = interval from first to last insemination in cows; CRc = conception rate at first insemination in cows.
  2. 2The left boundary of the QTL.
  3. 3The right boundary of the QTL.
  4. 4The number of significant SNPs within the QTL.
  5. 5The base pair position in the BTA (Bos taurus autosome).
  6. 6Minor allele frequency of the most significant SNP in Chinese and Nordic Holsteins.
  7. 7Genes harbor or closest to the most significant SNP.