Table 2 Forty-two differentially recognised antigens between resistant and susceptible individuals.

From: Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection

Antigen

p-value

p*

t

SE(t)

OR*

95% CI*

AUC

CT545

0.001

 < 0.001

8.38

2.63

9.05

2.57–39.71

0.78

CT118

0.003

0.002

6.40

2.18

8.18

2.19–37.48

0.78

CT123

0.004

0.001

6.43

2.21

8.7

2.23–43.16

0.76

CT541

0.006

0.004

6.09

2.21

6.74

1.85–28.71

0.78

CT664

0.009

0.008

5.76

2.20

6.36

1.71–28.27

0.80

CT119

0.009

0.007

5.19

1.98

4.35

1.51–14.00

0.76

CT381

0.010

0.009

5.03

1.96

4.56

1.48–15.49

0.76

CT584

0.012

0.010

6.90

2.75

6.3

1.62–29.64

0.76

CT284

0.012

0.009

6.34

2.53

4.83

1.51–18.22

0.74

CT502

0.014

0.012

6.46

2.62

5

1.50–19.93

0.80

CT051

0.017

0.015

5.06

2.11

5.44

1.47–24.26

0.74

CT592

0.019

0.018

4.14

1.77

3.6

1.28–11.23

0.75

CT073

0.020

0.017

6.01

2.58

6.91

1.47–39.52

0.77

CT078

0.020

0.018

6.07

2.61

4.88

1.38–20.58

0.74

CT023

0.022

0.019

6.60

2.88

7.61

1.56–51.76

0.77

CT223

0.022

0.020

5.93

2.59

4.11

1.31–15.14

0.76

CT795

0.024

0.018

3.91

1.73

3.67

1.23–11.93

0.76

CT875

0.028

0.030

5.14

2.34

4.21

1.22–16.47

0.73

CT181

0.030

0.024

4.32

1.99

4.05

1.20–15.42

0.75

CT694

0.031

0.031

3.91

1.81

3.68

1.17–12.78

0.74

CT021

0.034

0.033

5.45

2.57

4.72

1.19–21.77

0.77

CT813

0.035

0.033

3.50

1.66

3.13

1.12–9.57

0.75

CT841

0.036

0.035

3.77

1.80

3.15

1.12–9.78

0.74

CT017

0.036

0.039

3.77

1.80

4.37

1.16–18.92

0.75

CT142

0.036

0.037

4.24

2.03

3.41

1.12–11.48

0.74

CT764

0.037

0.034

5.74

2.75

4.5

1.18–20.92

0.78

CT728

0.039

0.040

4.86

2.35

3.97

1.14–16.23

0.78

CT228

0.039

0.037

5.54

2.69

4.34

1.16–19.64

0.74

CT703

0.040

0.042

4.82

2.34

5.76

1.20–34.90

0.74

CT494

0.040

0.037

5.63

2.74

5.62

1.19–32.96

0.76

CT106

0.041

0.039

5.87

2.87

3.45

1.11–12.30

0.76

CT097

0.041

0.040

5.50

2.70

3.6

1.10–13.26

0.75

CT316

0.043

0.049

6.00

2.96

3.66

1.10–14.02

0.75

CT579

0.044

0.041

3.73

1.85

3.55

1.09–13.26

0.77

CT168

0.044

0.044

6.32

3.14

5.37

1.19–32.48

0.76

CT089

0.044

0.045

4.54

2.26

3.34

1.07–11.61

0.75

CT237

0.045

0.043

5.79

2.88

4.53

1.13–22.39

0.75

CT806

0.046

0.046

4.89

2.45

3.49

1.08–12.84

0.76

CT668

0.048

0.049

5.68

2.87

3.45

1.07–12.91

0.77

CT642

0.048

0.047

5.80

2.93

3.39

1.08–12.52

0.76

CT695

0.049

0.053

3.73

1.90

3.44

1.06–12.84

0.75

CT570

0.050

0.049

5.92

3.02

4.29

1.08–20.48

0.76

  1. Univariate associations were determined using a generalised linear model. Variables were resampled 10,000 times and remodelled to determine permuted p-values (P*). Odds ratios (OR) and confidence intervals (CI) were calculated for an increase of half the range per antigen, rather than one unit. The predictive value of the univariate generalised linear models was calculated and presented as area under the curve (AUC).
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