Figure 6

Histology of ipsilateral joints in Arthritic TDAG8 knockdown mice. Samples of joints from shTDAG knockdown mice at 0, 4, 8, 12 weeks stained with hematoxylin and eosin are shown in (a-t). Data are mean ± SEM severity score for pannus (U), bone erosion (V), and cartilage damage (W). *p < 0.05, **P < 0.01, comparing (+)shTDAG8 vs (−)shTDAG8 by nonparametric Mann-Whitney U test.