Table 1 Body weight, kidney weight, and 24-h urinary albumin excretion in type I diabetes mellitus (DM) mice.

From: Periostin-binding DNA aptamer treatment attenuates renal fibrosis under diabetic conditions

 

C (N = 8)

C + PA (N = 8)

UNXSTZ (N = 8)

UNXSTZ + PA (N = 8)

Blood glucose (mg/dL)

264 ± 4.9

267 ± 6.2

576 ± 4.7*

587 ± 8.1*

Body Wt (g)

28.2 ± 6.3

26.9 ± 7.5

23.5 ± 2.5*

21.5 ± 4.3*

Kidney Wt (g)

0.12 ± 0.04

0.11 ± 0.06

0.23 ± 0.05*

0.19 ± 0.05*

Urinary albumin excretion (mg/day)

0.04 ± 0.01

0.05 ± 0.01

0.21 ± 0.08*

0.19 ± 0.05*

BUN (mg/dL)

22.0 ± 3.8

21.7 ± 1.2

39.3 ± 2.4*

30.5 ± 4.0**

  1. C, control; PA, periostin-binding DNA aptamer; UNXSTX, uninephrectomized STZ-induced DM mice; BUN, blood urea nitrogen. *P < 0.05 vs. C; **P < 0.05 vs. UNXSTX.
Back to article page