Table 1 Comparison of serum biochemistry analysis among groupsa, b.

From: Disease-syndrome combination modeling: metabolomic strategy for the pathogenesis of chronic kidney disease

 

Control group

Disease model group

DS model group

No. of subjects

10

10

12

Cholesterol, mmol/L

1.18 ± 0.20

2.56 ± 0.30**

2.66 ± 0.29**

Triglyceride, mmol/L

0.37 ± 0.10

0.57 ± 0.08**

0.37 ± 0.12ΔΔ

Lactate dehydrogenase, U/L

429.20 ± 89.17

1131.11 ± 122.93**

1111.86 ± 91.61**

Creatine kinase, U/L

225.80 ± 38.88

416.92 ± 95.67**

443.38 ± 80.69**

Blood urea nitrogen, mmol/L

7.40 ± 1.55

9.90 ± 1.06**

9.32 ± 1.13*

Creatinine, μmol/L

14.75 ± 2.75

54.60 ± 8.40**

55.29 ± 13.46**

  1. aThe serum levels of biochemical indices of rats are presented as the mean ± standard deviation. bThe serum concentrations of biochemical indices were statistically tested by Dunnett’s t-test when the variance in different groups was homogeneous and by the Games-Howell test when the variance was non-homogeneous. *P < 0.05, **P < 0.01 compared with the control group; Δ P < 0.05, ΔΔ P < 0.01 compared with the disease model group.
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