Figure 2 | Scientific Reports

Figure 2

From: Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata

Figure 2

Cell growth parameters determined by an algorithm-based automatic calculation for C. glabrata isolates exposed to anidulafungin. A total of 24 isolates, 2 with WT FKS genes, 6 with NWT FKS1 genes and 16 with NWT FKS2 genes were compared. For each group, growth parameters were evaluated in the isolates exposed to 0.06-µg/mL anidulafungin (AND) in comparison to the same isolates that were not exposed to the antifungal drug. Two subgroups of FKS2-NWTfast and FKS2-NWTslow isolates, i.e. identified within the FKS2-NWT isolates based on marked differences in their cell growth profiles, were also compared. The cell doubling times (in h) are measured at the maximal growth rate. The lag times (in h) represent the mean ± SD of three independent growth curves of cells exposed at the same time.

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