Table 2 The Correlation Coefficient between IL-6 and IL-6ST Depend on the Expression Level of IL-6R.
GEO datasets | All patients | Patients with IL6R expression in Top 25% | Patients with IL6R expression in bottom 25% | |||
|---|---|---|---|---|---|---|
r | P-value | r | P-value | r | P-value | |
GSE9891 | 0.112 | 0.084 | 0.400 | 0.001 | −0.058 | 0.661 |
GSE17260 | 0.305 | 0.001 | 0.413 | 0.029 | 0.119 | 0.546 |
GSE26193 | 0.112 | 0.250 | 0.264 | 0.182 | 0.097 | 0.629 |
GSE26712 | 0.264 | <0.001 | 0.377 | 0.009 | −0.039 | 0.797 |
GSE32062 | 0.417 | <0.001 | 0.526 | <0.001 | 0.304 | 0.014 |
GSE49997 | 0.246 | <0.001 | 0.212 | 0.142 | 0.283 | 0.049 |
GSE63885 | 0.069 | 0.555 | 0.145 | 0.553 | 0.035 | 0.886 |
TCGA | 0.186 | <0.001 | 0.175 | 0.038 | 0.294 | <0.001 |
Pooled r (95%CI) | 0.225 (0.141,0.305) | <0.001 | 0.310 (0.220,0.395) | <0.001 | 0.182 (0.087,0.274) | <0.001 |