Figure 5

Urinary pH and urea concentration in Protocol 2. Effect of intraperitoneal injection of luseogliflozin on urine pH (a) and urea concentration (b). SD, Sprague Dawley; Nx, 5/6 nephrectomized; vehicle, SD rats treated with vehicle; luseogliflozin, SD rats treated with luseogliflozin; Nx-vehicle, 5/6 Nx SD rats treated with vehicle; Nx-luseogliflozin, 5/6 Nx SD rats treated with luseogliflozin. Values are mean ± SEM. *P < 0.05 and ***P < 0.001 vs. baseline, ### P < 0.001 vs. vehicle.