Table 1 Comparison of characteristics of patients with HCC, CHB and healthy control in training and validation sets.

From: A Simple Noninvasive Index Can Predict Hepatocellular Carcinoma in Patients with Chronic Hepatitis B

Variables

Training Set (n = 224)

Validation Set (n = 239)

HCC (n = 76)

Healthy (n = 95)

CHB (n = 53)

HCC (n = 92)

Healthy (n = 69)

CHB (n = 78)

Gender

    Male (%)

58 (76)

58 (61)

40 (75)

75 (82)

54 (78)

61 (78)

    Female (%)

18 (24)

37 (39)

13 (25)

17 (18)

15 (22)

17 (22)

Age, years

57 ± 9

45 ± 10

46 ± 14

58 ± 8

53 ± 13

39 ± 12

White cell count (×109/L)

5.0 ± 2.0

6.2 ± 1.5

5.7 ± 2.4

4.4 ± 2.1

6.3 ± 1.1

5.9 ± 2.1

Red blood count (×1012/L)

4.3 ± 0.8

5.0 ± 0.5

4.5 ± 0.7

4.3 ± 0.8

5.0 ± 0.5

4.7 ± 0.7

Platelet count (×109/L)

132 ± 73

251 ± 51

165 ± 82

121 ± 67

250 ± 50

169 ± 64

Lymphocyte (×109/L)

1.3 ± 0.7

2.3 ± 0.7

1.7 ± 0.6

1.2 ± 0.6

2.1 ± 0.4

1.8 ± 0.6

Monocyte (×109/L)

0.4 ± 0.2

0.4 ± 0.1

0.5 ± 0.3

0.4 ± 0.2

0.4 ± 0.1

0.5 ± 0.2

Neutrophil (×109/L)

3.1 ± 1.5

3.3 ± 1.1

3.3 ± 2.0

2.7 ± 1.8

3.5 ± 1.0

3.4 ± 2.0

AFP (ng/ml)

372.6 ± 475.9

3.2 ± 1.6

94.4 ± 177.0

423.1 ± 645.9

3.4 ± 2.0

136.7 ± 260.6

AST (U/L)

82 ± 114

21 ± 7

316 ± 319

68 ± 110

24 ± 10

277 ± 277

ALT (U/L)

67 ± 101

22 ± 13

525 ± 716

49 ± 41

24 ± 18

474 ± 439

GGT (U/L)

147 ± 202

33 ± 23

129 ± 97

111 ± 134

30 ± 17

155 ± 157

ALP (U/L)

145 ± 74

83 ± 21

121 ± 61

148 ± 94

85 ± 21

131 ± 52

TBIL (umol/L)

37.1 ± 62.0

13.7 ± 5.8

104.8 ± 126.6

34.2 ± 40.1

15.6 ± 6.2

98.2 ± 124.0

BCLC stages

    0 (%)

5 (7)

  

11 (12)

  

    A (%)

18 (24)

  

25 (27)

  

    B (%)

23 (30)

  

26 (28)

  

    C (%)

30 (39)

  

29 (32)

  

    D (%)

0 (0)

  

1 (1)

  
  1. Values are expressed as mean ± SD. GGT, gamma-glutamyl transpeptidase; TBIL, total bilirubin.