Table 3 Accuracy of the APAR index in predicting HBV-related HCC in different cohorts of participants.

From: A Simple Noninvasive Index Can Predict Hepatocellular Carcinoma in Patients with Chronic Hepatitis B

Group(N)

APAR

CHB

HBV-related HCC

Sensitivity

Specificity

PPV

NPV

Totala (299)

<1.85

91

40

76.20%

69.50%

76.20%

69.50%

≥1.85

40

128

Low or normal AFPb (189)

<0.47

59

10

88.90%

59.60%

66.70%

85.50%

≥0.47

40

80

Normal AFPc (127)

<0.36

47

7

88.10%

69.10%

71.20%

87.00%

≥0.36

21

52

  1. aTotal cohort includes patients with CHB and HBV-related HCC in the training and the validation set. bParticipants with low or normal AFP includes CHB patients and HBV-related HCC in the whole set of participants with AFP < 100 ng/mL. cParticipants with low AFP includes CHB patients and HBV-related HCC in the whole set of participants with AFP < 20 ng/mL.