Figure 7 | Scientific Reports

Figure 7

From: Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

Figure 7

Olfactory expression of Vim and Phb subunits across AD stages. (a) Protein levels of Vim, Phb2, and Phb1 were monitored by Western-blotting. Equal loading of the gels was assessed by Ponceau staining and hybridization with a GAPDH specific antibody. Representative Western blot gels (n = 3/experimental group) are shown (left). Right panels show histograms of band densities. Data are presented as mean ± SEM from 3 independent OB samples per group. *P < 0.05 vs control group; ***P < 0.001 vs control group. (b) OB phosphorylation profiling of PHb1 across AD staging. Representative Western blot gels (n = 2/experimental group) are shown (left). Right panel shows histograms of band densities. Data are presented as mean ± SEM from 3 independent OB samples per group. *P < 0.05 vs control group; **P < 0.01 vs control group. Full-length blots/gels are presented in Supplementary information.

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