Figure 6
Gradual unfolding of the FnIII3 domain of CNTN4. Snapshots from simulations at various time points of the mechanical unfolding are shown. The accompanying time evolution of force is shown on the upper right. (b) Schematic structure of FnIII3 domain of CNTN4. Colors denote the sequence of unfolding events. (c) Change in the number hydrogen bonds traced during the course of stress-induced unfolding for 5 pairs of β-strands making hydrogen bonds in the folded state.
