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Figure 1

From: Methylseleninic Acid Provided at Nutritional Selenium Levels Inhibits Angiogenesis by Down-regulating Integrin β3 Signaling

Figure 1

Uptake and metabolism of MSA by HUVECs. (A) Se concentrations in medium or cells treated with/without 2 μM MSA for different hours (0, 0.5, 6, 12, 24, 48 h) were detected by AFS. The error bars represented the SD (n = 3). (B) Se metabolites of HUVECs exposed to 2 μM MSA for different hours (0, 0.5, 6, 12, 24 h) were detected by HPLC-ICP-MS, and different selenium standards including MSA, SeMet, SeMC, and DMSe were used as positive control. Peak identification: (1) MSA, (2) SeMC, (3) SeMet, (4) DMSe, (5) Unknown.

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