Figure 5 | Scientific Reports

Figure 5

From: A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling

Figure 5

Modulation of FZD4 expression by WNT and FZD4 protein interaction in rs713065 variants in H1299 cells. (A) Interaction of Wnt ligands and FZD4 receptor in H1299 cells transfected with Wnt-5A-V5 and FZD4-FLAG expression plasmids shown by confocal fluorescence imaging. (B) rs713065 (C) down-regulates FZD4, as quantitatively measured by confocal microscopy.

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