Table 1 The five top WNT pathway regulators identified by IPA and downregulated by the rs713065/C allele (see Supplementary Table 2 for IPA summary).

From: A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling

Upstream Regulator

p-Value of overlap

Predicted Activation

NOTCH1

4.00E-26

Inhibited

ERBB2

1.57E-25

Inhibited

STAT3

7.60E-25

Inhibited

CTNNB1

8.27E-25

Inhibited

HRAS

8.48E-24

Inhibited