Table 1 The five top WNT pathway regulators identified by IPA and downregulated by the rs713065/C allele (see Supplementary Table 2 for IPA summary).
Upstream Regulator | p-Value of overlap | Predicted Activation |
|---|---|---|
NOTCH1 | 4.00E-26 | Inhibited |
ERBB2 | 1.57E-25 | Inhibited |
STAT3 | 7.60E-25 | Inhibited |
CTNNB1 | 8.27E-25 | Inhibited |
HRAS | 8.48E-24 | Inhibited |