Table 2 Results of region of interest (ROI) analysis during rectal distention.

From: Altered brain and gut responses to corticotropin-releasing hormone (CRH) in patients with irritable bowel syndrome

Side

Region

Between group

Within-group

Control

IBS

Control > IBS

IBS > Control

Positive

Negative

Positive

Negative

R

mPFC

 >0.1

0.009*

 >0.1

0.047*

 >0.1

 >0.1

L

mPFC

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

R

pACC

 >0.1

 < 0.001*

 >0.1

0.018*

0.082

 >0.1

L

pACC

 >0.1

 < 0.001*

 >0.1

0.004*

 >0.1

 >0.1

R

Hippocampus

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

L

Hippocampus

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

R

Amygdala

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

L

Amygdala

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

 >0.1

  1. Corrected p values are presented and * indicates significant p value, IBS: irritable bowel syndrome; pACC: pregenual anterior cingulate cortex; mPFC: medial prefrontal cortex.
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