Figure 3
Heterogeneity of quaternary structures available in the Protein Data Bank (PDB). Assemblies from the PDB were clustered by sequence identity (90% sequence identity). All the assemblies within one sequence cluster were compared using QS-score. The resulting distance matrix was used to perform hierarchical clustering using different distance thresholds. With a distance threshold (x-axis) of 0 all assemblies are clustered together so that the fraction of sequence clusters (y-axis) having only one QS cluster is 100%. As the threshold is increased the structural heterogeneity of the sequence clusters is evident and the fraction of sequence clusters having multiple QS clusters (in shades of blue) increases.
