Figure 4
From: Neuroprotective effect of kinin B1 receptor activation in acute cerebral ischemia in diabetic mice
B1R-ag had no effect on neurological impairment, mortality and infarct size 48 h after transient MCAO in NonDiab mice. (a) Neurological score (0–30) measured in NonDiab mice, treated with B1R-ag (720 nmol/kg.day−1) (grey bars) or saline (black bars), at day 0, 1 and 2 after transient MCAO or sham-operation. (b) Survival curve of NonDiab mice treated with B1R-ag or non-treated after transient MCAO. Numbers in parentheses refer to surviving/operated animals. (c) Ischemic area measured at 48 h after transient MCAO using TTC staining. Values are mean ± SEM, n = 9–14/group. **p < 0.01 vs non ischemic group.
