Figure 2
From: Intracellular Chloride Regulation in AVP+ and VIP+ Neurons of the Suprachiasmatic Nucleus
GABAA receptor-mediated Cl− transients in AVP+ and VIP+ neurons. Top row: AVP+ neurons from AVP::Cl-Sensor mice tested during subjective day (left) and subjective night (right) demonstrated an increase of RCl following puff application of the GABAA agonist isoguvacine (gray arrow), indicative of inhibitory Cl− influx. Similarly, VIP+ neurons from VIP::Cl-Sensor mice during both day and night responded to isoguvacine with an increase of RCl (bottom row). Each trace represents a RCl measurement obtained from a single neuronal soma.
