Table 3 Performance of the BYG Carba v2.0 according to carbapenemase family.

From: Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae

 

Retrospectively (n = 511) Spec: 100% (CI95: 97.1–100)

Prospectively (n = 670) Spec: 99.7% (CI95: 97.9–100)

Total (n = 1181) Spec: 99.7% (CI95: 98.6–100)

Sens (%) (CI95)

Sens (%) (CI95)

PPV (%) (CI95)

NPV (%) (CI95)

Sens (%) (CI95)

CPE

94.8 (91.8–96.8)

97.7 (95.4–98.9)

99.7 (98.2–100)

97.5 (94.9–98.8)

96.3 (94.5–97.5)

OXA-48-like

96.1 (90.6–98.5)

97.8 (94.8–99.2)

99.6 (97.2–100)

98.4 (96.1–99.4)

97.2 (94.8–98.6)

KPC

100 (93.6–100)

100 (89.8–100)

97.7 (86.5–99.9)

100 (98.5–100)

100 (95.9–100)

NDM

93.3 (83.0–97.8)

97.9 (87.3–99.9)

97.9 (87.3–99.9)

99.7 (97.9–100)

95.3 (88.9–98.2)

VIM

98.1 (88.4–99.9)

92.3 (73.4–98.6)

96.0 (77.7–99.8)

99.4 (97.4–100)

96.1 (88.4–99.0)

IMP

86.7 (58.4–97.6)

100 (19.8–100)

66.7 (12.5–98.2)

100 (98.5–100)

88.2 (62.2–97.9)

OXA-48-like + NDM

100 (59.8–100)

100 (51.7–100)

85.7 (42.0–99.2)

100 (98.5–100)

100 (73.2–100)

  1. The values are based on the results reported by each centre without any correction of the discrepancies by the CHU UCL Namur.
  2. Sens: sensitivity; Spec: specificity; PPV: positive predictive value; NPV: negative predictive value.
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