Figure 1

Venn diagram showing the proportions of Mycobacterium tuberculosis blood culture positive patients (n = 41) who had a TB diagnosis made by rapid microbiological tests. (A) Sputum-based diagnostics and (B). Urine-based diagnostics. Percentages represent the proportion of patients with positive mycobacterial blood culture diagnosed by a respective test and ‘n’ is the actual number of patients with positive mycobacterial blood culture diagnosed by a respective test. Any proportion (n) within the red portion was not diagnosed by any test, i.e. was exclusively detecting using mycobacterial blood culture. AFB = acid fast bacilli, LAM = Lipoarabinomannan. *Both sputum Xpert and sputum microscopy had identical diagnostic yield. Sputum microscopy and sputum Xpert had identical diagnostic yield for Mycobacterium tuberculosis bacteraemia and both tests diagnosed n = 3/9 Mycobacterium tuberculosis blood culture positive patients who died within 90 days.