Table 2 Multinomial logistic regression of risk factors for M. tuberculosis blood culture positivity*.

From: Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays

 

Unadjusted RR (95%CI)

p-value

Adjusted RR (95% CI)

p-value

Age, for each year increase

0.95 (0.91–0.98)

0.004

0.95 (0.90–1.00)

0.040

Female

1.13 (0.58–2.22)

0.71

  

New HIV status

2.21 (1.09–4.50)

0.036

0.91 (0.36–2.27)

0.83

ART status

Current use

1.0

0.24

  

Naïve

1.81 (0.88–3.74)

   

Defaulted

1.18 (0.43–3.25)

   

Previous history of TB treatment

No

1.0

0.17

  

Yes

0.63 (0.09–0.20)

   

Current cough

No

1.0

0.027

1.0

0.43

Yes

2.10 (1.08–4.09)

 

1.41 (0.59–3.36)

 

Current weight loss

No

1.0

0.012

1.0

0.14

Yes

2.17 (1.12–4.20)

 

4.20 (0.70–25.39)

 

Current fever

No

1.0

0.38

  

Yes

1.47 (0.64–3.36)

   

Current night sweats

No

1.0

0.030

1.0

0.25

Yes

2.05 (1.07–3.93)

 

0.33 (0.05–2.01)

 

CD4 (cells/μL), for every 50 unit decrease

1.61 (1.29–2.01)

<0.001

1.32 (1.05–1.66)

0.004

Viral load (copies/mL), for each log unit increase

1.50 (1.18–1.90)

0.003

1.20 (0.89–1.63)

0.23

Haemoglobin (g/dL), for each unit decrease

1.40 (1.22–1.60)

<0.001

1.30 (1.09–1.56)

0.003

Platelet (×10 9 cells/L), for each 10 unit decrease)

1.03 (1.01–1.06)

<0.001

1.03 (0.99–1.06)

0.10

Sodium (mmol/L), for each 1 unit decrease

1.06 (0.99–1.14)

0.11

  

CRP (mg/L), for each 10 unit increase

1.06 (1.03–1.10)

<0.001

1.06 (1.01–1.10)

0.013

eGFR (mL/min/1.73m 2 ), for each unit decrease

0.99 (0.94–1.04)

0.60

  
  1. *Among 410 patients with mycobacterial blood culture results available.