Table 1 Clinical characteristics of sepsis patients and healthy controls.
Variable | Sepsis (n = 403) N(%) | Control (n = 400) N(%) | P value |
|---|---|---|---|
Demographics | |||
Age, years, mean ± SD | 59.09 ± 16.66 | 57.47 ± 13.71 | 0.110 |
Male/female, number | 286/117 | 271/129 | 0.323 |
Sepsis status, n(%) | |||
Mild sepsis | 74(18.4) | N.A | |
Severe sepsis | 191(47.4) | N.A | |
Septic shock | 138(34.2) | N.A | |
Source of infection, n(%) | |||
Respiratory tract infection | 254(63.0) | N.A | |
Primary bloodstream infection | 48(11.9) | N.A | |
Abdominal infection | 94(23.3) | N.A | |
Urinary tract infection | 22(5.5) | N.A | |
Catheter-associated infection | 14(3.5) | N.A | |
Brain | 29(7.2) | N.A | |
Others | 35(8.7) | N.A | |
Infection types, n(%) | |||
Gram-positive | 40(9.9) | N.A | |
Gram-negative | 135(33.5) | N.A | |
Mixed Gram-negative and -positive | 47(11.7) | N.A | |
Fungus | 87(21.6) | N.A | |
Polymicrobial | 64(15.9) | N.A | |
Negative blood culture | 31(7.7) | N.A | |
Pathogenic bacteria, n(%) | |||
Acinetobacter baumannii | 93(23.1) | N.A | |
Monilia albican | 27(6.7) | N.A | |
Yeast sample sporphyte | 26(6.5) | N.A | |
Aspergillus | 17(4.2) | N.A | |
Klebsiella pneumoniae | 26(6.5) | N.A | |
Pseudomonas aeruginosa | 39(9.7) | N.A | |
Staphylococcus aureus | 33(8.2) | N.A | |
Escherichia coli | 44(10.9) | N.A | |
Others | 76(18.9) | N.A | |
APACHE II score | 23.8 ± 7.1 | N.A | |
28-day mortality, n(%) | 102(25.3) | N.A | |