Table 1 Clinical characteristics of sepsis patients and healthy controls.

From: Association between genetic polymorphisms in the autophagy-related 5 gene promoter and the risk of sepsis

Variable

Sepsis (n = 403) N(%)

Control (n = 400) N(%)

P value

Demographics

Age, years, mean ± SD

59.09 ± 16.66

57.47 ± 13.71

0.110

Male/female, number

286/117

271/129

0.323

Sepsis status, n(%)

Mild sepsis

74(18.4)

N.A

 

Severe sepsis

191(47.4)

N.A

 

Septic shock

138(34.2)

N.A

 

Source of infection, n(%)

Respiratory tract infection

254(63.0)

N.A

 

Primary bloodstream infection

48(11.9)

N.A

 

Abdominal infection

94(23.3)

N.A

 

Urinary tract infection

22(5.5)

N.A

 

Catheter-associated infection

14(3.5)

N.A

 

Brain

29(7.2)

N.A

 

Others

35(8.7)

N.A

 

Infection types, n(%)

Gram-positive

40(9.9)

N.A

 

Gram-negative

135(33.5)

N.A

 

Mixed Gram-negative and -positive

47(11.7)

N.A

 

Fungus

87(21.6)

N.A

 

Polymicrobial

64(15.9)

N.A

 

Negative blood culture

31(7.7)

N.A

 

Pathogenic bacteria, n(%)

Acinetobacter baumannii

93(23.1)

N.A

 

Monilia albican

27(6.7)

N.A

 

Yeast sample sporphyte

26(6.5)

N.A

 

Aspergillus

17(4.2)

N.A

 

Klebsiella pneumoniae

26(6.5)

N.A

 

Pseudomonas aeruginosa

39(9.7)

N.A

 

Staphylococcus aureus

33(8.2)

N.A

 

Escherichia coli

44(10.9)

N.A

 

Others

76(18.9)

N.A

 

APACHE II score

23.8 ± 7.1

N.A

 

28-day mortality, n(%)

102(25.3)

N.A

 
  1. N.A: not applicable; APACHE II: Acute Physiology and Chronic Health Evaluation II; Continuous data are expressed as the mean ± SD.