Table 3 Genotype and allele frequencies distribution between 28-day surviving and non‐surviving sepsis patients.
SNP | Survivors n = 301(%) | Non-survivors n = 102(%) | P | P* | OR (95% CI) |
|---|---|---|---|---|---|
rs510432/rs506027 | |||||
GG/TT | 109(36.2) | 26(25.5) | 0.125 | 0.167 | — |
GA/TC | 149(49.5) | 57(55.9) | — | — | — |
AA/CC | 43(14.3) | 19(18.6) | — | — | — |
GG + GA/TT + TC | 258(85.7) | 83(81.4) | 0.294 | 0.294 | 1.373(0.758, 2.488) |
GA + AA/TC + CC | 192(63.8) | 76(74.5) | 0.047 | 0.118 | 0.603(0.364, 0.997) |
G/T | 367(61.0) | 109(53.4) | 1.000 (reference) | ||
A/C | 235(39.0) | 95(46.6) | 0.059 | 0.118 | 0.735(0.533, 1.012) |
rs548234 | |||||
TT | 159(52.8) | 51(50.0) | 0.731 | 0.731 | — |
TC | 122(40.5) | 42(41.2) | — | — | — |
CC | 20(6.7) | 9(8.8) | — | — | — |
TT + CT | 281(93.4) | 93(91.2) | 0.462 | 0.731 | 1.360(0.598, 3.091) |
CT + CC | 142(47.2) | 51(50.0) | 0.622 | 0.731 | 0.893(0.570, 1.400) |
T | 440(73.1) | 144(70.6) | — | — | |
C | 162(26.9) | 60(29.4) | 0.490 | 0.731 | 0.884(0.622, 1.255) |
rs10210302/rs2241880 | |||||
CC/AA | 143(47.5) | 39(38.2) | 0.258 | 0.344 | — |
CT/GA | 123(40.9) | 50(49.0) | — | — | — |
TT/GG | 35(11.6) | 13(12.8) | — | — | — |
CC + CT/AA + GA | 266(88.4) | 89(87.3) | 0.763 | 0.763 | 0.110(0.562, 2.192) |
CT + TT/GA + GG | 158(52.5) | 63(61.8) | 0.104 | 0.348 | 0.684(0.432, 1.082) |
C/A | 409(67.9) | 128(62.7) | — | — | 1.000 (reference) |
T/G | 193(32.1) | 76(37.3) | 0.174 | 0.348 | 0.795(0.571, 1.107) |
