Figure 1

ND-PTX inhibits cell viability in various human CRC cells. (a) The human CRC cell lines (HCT116, SW620 and RKO) were left treated with or without NDs (1–50 μg/mL for 24 h). The cellular morphology was observed under a phase contrast microscope. (b) The cell viability after treatment with NDs was determined by MTT assays. (c) The cells were left treated with or without ND-PTX (0.1–10 μg/mL for 48 h). The cell viability was determined by MTT assays. The results were obtained from three separate experiments. The bars represent mean ± S.E. *p < 0.05 and **p < 0.01 indicate significant difference between untreated and ND-PTX treated samples.